Quantifying Prostate Cancer Lesions via PSMA-PET
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Other organizations : The Netherlands Cancer Institute
Variable analysis
- No independent variables explicitly mentioned.
- SUV_max (maximum standardized uptake value) of the most clinically suspect prostatic lesion in each patient, normalized for body weight.
- SUV_max was measured according to the E-PSMA criteria and was compliant with EARL standards.
- Volumes-of-interest (VOIs) were manually drawn at least 1.5 cm in diameter over the index lesion, carefully omitting physiological activity from the urethra or bladder.
- If no PSMA expression suspect for PCa was detected by the nuclear medicine physician, a VOI was drawn over the prostate location corresponding with a suspect lesion on multiparametric MRI (mpMRI), when available.
- To cross-validate both measuring software programs, identical scans from four patients were analysed with both programs, with 100% agreement.
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