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Profiling PI3K/AKT/mTOR Pathway Signatures

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Zhang Y., Ng P.K., Kucherlapati M., Chen F., Liu Y., Tsang Y.H., de Velasco G., Jeong K.J., Akbani R., Hadjipanayis A., Pantazi A., Bristow C.A., Lee E., Mahadeshwar H.S., Tang J., Zhang J., Yang L., Seth S., Lee S., Ren X., Song X., Sun H., Seidman J., Luquette L.J., Xi R., Chin L., Protopopov A., Westbrook T.F., Shelley C.S., Choueiri T.K., Ittmann M., Van Waes C., Weinstein J.N., Liang H., Henske E.P., Godwin A.K., Park P.J., Kucherlapati R., Scott K.L., Mills G.B., Kwiatkowski D.J, & Creighton C.J. (2017). A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations. Cancer cell, 31(6), 820-832.e3.
Publication 2017
4ebp1 Akt inhibitor viii Akt1 Azd6482 Azd8055 Breast cancer Cancer Chir 99021 Drug Gdc0941 Genes Gsk3 Inhibitors Mk 2206 Mouse Mtor Mtor inhibitors Mtorc1 Nvp bez235 P70s6k Phosphoprotein Pi3k Pten Pten protein Rapamycin Sensitivity Temsirolimus Tissue Transcriptional Tsc2 Tumor

Corresponding Organization : Massachusetts Institute of Technology

Other organizations : Dana-Farber Cancer Institute, Research Institute Hospital 12 de Octubre, Center for Systems Biology, University of Wisconsin–Madison, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, University of Kansas Medical Center

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