After the randomization procedure, patients were allocated to either the study or control group. Both groups were required to take blood samples of 25-OH-vitamin D and calcium, and they followed through with the standard treatment procedure. The standard treatment procedure was based on fracture complexity but included casting, closed reduction, and open reduction. X-ray and clinical follow-ups were done after 1 day, 3 weeks, 5 weeks, 2 months, 6 months, and 1 year.
Patients in the study group were asked to perform the following blood tests: 25-OH-vitamin D and total calcium. They repeated them after 6 months of supplementation.
For vitamin D, the values for 25-OH-vitamin D were classified with standard laboratory values as follows: toxic value: over 100 ng/mL, normal value: between 30 ng/mL and 100 ng/mL, poor value: between 20 ng/mL and 29 ng/mL, and insufficient value: less than 20 ng/mL. For calcium, the values of total calcium were considered as follows: hypercalcemia: over 10.6 mg/dL; normal value: between 8.80 mg/dL and 10.6 mg/dL.
The following therapeutic interventions were applied to the study group for the following 6 months if vitamin D was less than 30 ng/mL: oral treatment: patients would receive vitamin D [2000 I.U./day] and calcium [600 mg/day] in the first part of the day.
The control group performed blood tests at the beginning of the study and was monitored clinically and radiologically for fracture healing and functional outcomes.
The study duration was at least one year for each patient included.
Patients in the study group were asked to perform the following blood tests: 25-OH-vitamin D and total calcium. They repeated them after 6 months of supplementation.
For vitamin D, the values for 25-OH-vitamin D were classified with standard laboratory values as follows: toxic value: over 100 ng/mL, normal value: between 30 ng/mL and 100 ng/mL, poor value: between 20 ng/mL and 29 ng/mL, and insufficient value: less than 20 ng/mL. For calcium, the values of total calcium were considered as follows: hypercalcemia: over 10.6 mg/dL; normal value: between 8.80 mg/dL and 10.6 mg/dL.
The following therapeutic interventions were applied to the study group for the following 6 months if vitamin D was less than 30 ng/mL: oral treatment: patients would receive vitamin D [2000 I.U./day] and calcium [600 mg/day] in the first part of the day.
The control group performed blood tests at the beginning of the study and was monitored clinically and radiologically for fracture healing and functional outcomes.
The study duration was at least one year for each patient included.
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