Sucrose preference test was performed to assess hedonic behaviour towards a sweet gustatory stimulus11 (link). Mice were given access to two water bottles (50 ml conical tubes with sipper tops) for 24 h for habituation. Then, one water bottle was exchanged with a bottle containing 1% sucrose (Sigma, S0389) in drinking water. After 24 h, the bottle positions were swapped to prevent position bias. After another 24 h, sucrose preference was assessed as follows (based on weight of bottles): (sucrose (g)/total fluid (g)) × 100%.
Corresponding Organization : Icahn School of Medicine at Mount Sinai
Other organizations :
Tisch Hospital, Allen Institute for Brain Science, Universidade Federal de Santa Catarina, Center for Discovery, Trinity College Dublin
Sucrose preference (calculated as (sucrose (g)/total fluid (g)) × 100%)
control variables
Habituation period (24 h with access to two water bottles)
Bottle position (swapped after 24 h to prevent position bias)
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