Bacterial Meningitis Diagnosis Protocol

Patients ≥ 18 years of age presenting with clinical disease suggesting bacterial meningitis (headache, fever, stiffness of the neck, petechiae, confusion or impaired level of consciousness) in combination with one or more of the following:
Bacterial meningitis with unknown pathogen was included based on the clinical criteria above in combination with the following CSF biochemistry: >10 x 10⁶ cells/L) in combination with low CSF glucose or glucose-ratio (<2.0 mmol/L and 0.3 respectively) or CSF lactate >3.5 mmol /L.

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Thomsen M.M., Munthe-Fog L., Trier Petersen P., Hillig T., Friis-Hansen L.J., Roed C., Harboe Z.B, & Brandt C.T. (2023). Pentraxin 3 in the cerebrospinal fluid during central nervous system infections: A retrospective cohort study. PLOS ONE, 18(3), e0282004.

Publication 2023

Bacterial meningitis Cells l Consciousness Fever Glucose Headache Lactate Meningitis Neck Pathogen Patients Petechiae Unknown bacterial

Corresponding Organization : University of Copenhagen

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Variable analysis

independent variables

Patients ≥ 18 years of age presenting with clinical disease suggesting bacterial meningitis (headache, fever, stiffness of the neck, petechiae, confusion or impaired level of consciousness)

dependent variables

CSF biochemistry: >10 x 10^6 cells/L in combination with low CSF glucose or glucose-ratio (<2.0 mmol/L and 0.3 respectively) or CSF lactate >3.5 mmol /L

control variables

Independent variables not explicitly mentioned.
Dependent variables not explicitly mentioned.
Control variables not explicitly mentioned.

controls

No positive or negative controls were specified by the authors.

Annotations

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